问题 问答题 简答题

试述阿托品的基本药理作用和临床用途。

答案

参考答案:

阿托品为M胆碱受体阻滞药,具有广泛的药理作用和用途:

(1)解除平滑肌痉挛,缓解内脏绞痛。

(2)眼科应用:阿托品能阻断虹膜括约肌和睫状肌上的M受体,导致扩瞳和调节麻痹,可用于扩瞳和治疗虹膜睫状体炎及验光配镜。

(3)抑制腺体分泌:常用于全身麻醉前给药,减少呼吸道分泌,防止分泌物阻塞呼吸道和吸入性肺炎的发生,亦可用于严重盗汗和流涎症。

(4)增快心率,加速房室传导:阿托品能阻断迷走神经对心脏的抑制,故临床常用阿托品治疗缓慢型心律失常如窦性心动过缓、房室阻滞等。

(5)解除小血管痉挛,改善微循环:阿托品的这种作用与抗M胆碱受体作用无关。大剂量阿托品用于治疗感染中毒性休克。

(6)解救有机磷酸酯类中毒的首选药。

阅读理解

阅读理解

    "When one of the doctors criticizes (批评) me, I get defensive.I feel like a child again, being scolded,

and I want to explain that I'm not wrong, " says Viola, a nurse.This is a common reaction to criticism, but

not a good one.There are better ways of dealing with criticism.

     Try to be objective (客观的). When Sol was criticized by his new employer for not having made a

sale, Sol's reaction was to feel sorry for himself."I had put everything I had into making that sale, " Sol

says."And I felt that I had failed as a person.I had to learn through experience not to react like that to

each fail ure."

     Take time to cool down.Rather than react at once to criticism, take some time to think over what was

said.Your first question should be whether the criticism is fair from the other person's position.The

problem may be a simple misunderstanding of what you did or your reasons for doing it.

     Take positive action.After you cool down, consider what you can do about the situation.The best

answer may be "nothing". "I finally realized that my boss was having personal problems and taking them

out on me because I was there, " says Sheila."His criticisms didn't really have anything to do with my

work, so nothing I said or did was going to change them." In Sheila's case, the best way to deal with it

was to leave her job.However, that's an extreme reaction.

     You may simply explain your opinion without expecting an indepth discussion.You may even decide

that the battle isn't worth fighting this time.The key, in any case, is to have a reasonable plan.

1. When Sol was criticized by his employer, he________.

A. argued bitterly with his employer

B. was angry and gave up his job

C. was sorry for what he did

D. was sad and selfpitying

2. According to the writer, you should take time to think about criticism because________.

A. people may have a mistaken idea of what you did

B. you should welcome other people's opinions

C. people may discuss it with you in depth

D. you need time to understand yourself

3. When the writer says that "The best answer may be 'nothing'", he means you may decide________.

A. to take no notice of the criticism

B. to argue with your boss

C. you need to change your job

D. you've done nothing wrong

4. The writer thinks Sheila might decide to leave her job because her boss________.

A. didn't like her appearance

B. refused to change his opinion

C. made an unreasonable criticism

D. refused to talk to her about the criticism

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