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问题 单项选择题

盐酸多柔比星，又称阿霉素，是光谱抗肿瘤药物其化学结构如下：

临床上，使用盐酸多柔比星注射液时，常发生骨雖抑制和心脏毐性等严重不良反应，解决方法之一是将其制成脂质体制剂。盐酸多柔比星脂质体注射液的辅料有PEG-DSPE，氢化大豆卵磷脂，胆固酵，硫氨酸，蔗糖，组氨酸等

盐酸多柔比星毒性作用主要是骨髓抑制和心脏毐性，产生这一毒副作用的原因可能是（）。

A.在体内发生脱甲基化反应

B.在体内容易进一步氧化，生产的醛基代谢物具有较大毒性

C.在体内发生醌环易被还原成半醌自由基，诱发脂质过氧反应

D.在体内发生氨基糖开环反应，诱发脂质过氧反应

E.在体内发生脱水反应，代谢具有较大毒性

答案

参考答案：C

多项选择题

灰土地基验收标准的主控项目中，( )必须达到设计要求值。

A．低级承载力

B．石料粒径

C．灰土配合

D．砂石料有机含量

E．压实系数
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单项选择题

In June 1985, two British mountaineers Joe Simpson and Simon Yates made the first-ever climb of the 21,000-foot snow-covered Siula Grande mountain in Peru. It was an exceptionally (26) job, but nothing compared to what was to (27) . Early in the process, Simpson (28) and broke his right knee. Yates could have (29) him but managed to find a way of (30) him down the mountains on a rope in a series of difficult drops. Then Simpson fell into a crevasse and Yates eventually had no (31) but to cut the (32) , completely convinced that his friend was now (33)

In his book on the (34) , Joe Simpson wrote:

(35) I looked at the distant moraines, I know that I must at least try I would probably (36) there among those rocks. If I died, well, that wasn’t so (37) , but I wouldn’t have (38) waited for it to happen. The (39) of dying no longer affected me as it had in the crevasse at first. I now had a chance to (40) it and struggle against it.

The survival of Yates himself was (41) . That Simpson somehow found a way of (42) out of the crevasse after 12 hours and then crawled and (43) himself six miles back to camp, (44) three days and might without food or drink, would be considered as a heroic fiction. But in fact it was so (45) .

38().

A. ever

B. just

C. almost

D. never
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