对于糖尿病大血管病变正确的是（）

A.脑动脉硬化常表现为脑血栓形成

B.冠心病引起急性心肌梗死

C.肢体动脉硬化可引起下肢疼痛，间歇性跛行，肢端坏疽

D.冠心病和急性脑血管病的患病率较非糖尿病者高2～3倍

E.大血管病是糖尿病的特征性改变

There is _____ work for me to do. I am really tired. [ ]

A. too many

B. too much

C. many too

D. much too