— Why were you late for the meeting yesterday?

— Well, my car ________ on the way to the company. [ ]

A. broke out  

B. broke down

C. broke up    

D. broke through

患者女性，59岁，以双膝关节、腰部疼痛7个月来诊。疼痛于劳累及久站后加重，休息后减轻。查体：双手可见Heberden结节，膝关节略肿胀，活动时可闻骨擦音，活动轻微受限。腰椎14—L5棘突两侧压痛阳性。化验：ESR10mm/1h，CRP 5mg/L，RF阴性，ANA阴性。

该患者化验检查血清补体、免疫球蛋白及尿酸均正常，推测X线可能的表现，应包括以下哪项

A．膝关节间隙变窄

B．膝关节软骨下骨质硬化及囊性变

C．膝关节半脱位

D．腰椎唇样骨赘

E．膝关节边缘骨赘形成