Such good use has been ________ his spare time ________ his English has improved a lot.[ ]

A. made of；as  

B. made of；that

C. made in；that  

D. made from；as

患者男性，53岁，主诉腰痛3年加重伴有右下肢放射痛1周。查体：上肢肌力正常，右踝及趾背伸肌力下降，双侧腱反射及跟腱反射正常，双侧病理征（-）。

患者病变最可能受累的神经是（）

A.腰2神经

B.腰3神经

C.腰4神经

D.腰5神经

E.骶1神经