句型转换。

1. Have you packed the beach towels yet?(作否定回答）

    _______ , _______ _______.

2. Mary has already cleaned the room. (改为一般疑问句)

    Mary_______ the room_______?

3. He came here three days ago.(改为同义句)

    He has _______here _______three days.

4. I left Beijing three months ago.(改为同义句)

    Bei Jing_______three months.

5. I have lived in Shanghai since l was born.(对画线部分提问)

    _______ _______have you lived in Shanghai?

* * 下裂的主要原因是由于（）

A.父亲酗酒过度

B.孕期母亲接触农药

C.孕期母亲接触X线

D.孕期母亲吸烟过多

E.胎儿期睾酮缺乏或作用不足