Lloyd's, an association of London underwriters, developed from a small seventeenth century London coffee house, ______ underwriters at that time met to do business.

A．where
B．in that
C．which
D．that

不属于细胞因子作用特点的是哪一项（）

A.多效性

B.协同性

C.多向性

D.特异性

E.旁泌性