They stood there with their eyes____ , watching over what was happening.[    ]

A. wide open  

B. wide opened      

C. widely open    

D. widely opened

神经纤维瘤病变主要为起源于__________的多发性神经纤维瘤，可累及________和_________。引起的症状依侵犯不同的神经有所不同，常可致____________和___________，皮肤受累主要表现为____________。