With so much work _______, we had to sit up through the night.[ ]

A. done          

B. doing               

C. to do                

D. being done

下列哪项不是雌激素减少所导致的（）。

A.促钙和磷沉积作用减弱

B.促骨基质合成功能减弱

C.拮抗甲状旁腺素作用减少

D.降钙素分泌增加

E.促进维生素