At a rough estimate（估计）, Nigeria is ____ Great Britain.

A．three times the size as

B．the size three times of

C．three times the size of

D．three times as the size of

男性，34岁，1周前左足底被铁钉刺伤，自行包扎，昨夜突感胸闷、紧缩感，晨起，张口困难和抽搐、诊断为破伤风。

破伤风是破伤风杆菌所致的（）。

A.菌血症

B.败血症

C.脓血症

D.毒血症

E.脓毒败血症