正常细胞转变为肿瘤细胞后具有（）

A.异常的形态、代谢核功能

B.不同程度的失去了分化成熟的能力

C.生长旺盛，具有相对的自主性

D.增生过程中致瘤因素不存在时能持续生长

E.与机体不协调且有害

Due to a constantly (71) environment, a poor understanding of the user’s needs and preferences, as well as a (72) of willingness to modify (73) organizational structures and decision models, the full economic potential of Web.
Information Systems (WIS) has not been realized by now. The data object types of the (74) meta model, the Extended World Wide Web Design Technique (EW3DT), provide hypertext designers (75) a conceptual, user-centric framework and graphical notation for the construction of both, reference and customized models, during the software development process of commercial WIS. A reference model as a normative concept represents an abstraction of a typical company, its functional units, or its (Web) Information Systems and is intended to streamline the design and implementation of complex applications at reduced costs. As precondition for pursuing a partial globalization strategy, EW3DT distinguishes between technical and content-specific responsibilities for designing, implementing, and maintaining WIS.

A．give

B．above

C．presented

D．got