46 Our manager allowed _______to take a holiday next week.

A．you and I

B．yourself and me

C．I and you

D．you and me

预防牙周疾病、控制局部相关危险因素的措施是（）

A.降低牙尖高度和斜度

B.去除不良修复体

C.补充维生素和钙磷等营养

D.治疗食物嵌塞

E.去除充填悬突