女性，40岁，3个月前精神受刺激，3个月来睡眠差。常口渴难忍，夜间亦需大量饮水，每日饮水4~5暖壶，喜饮凉水。尿量明显增加，平均每小时排尿一次，夜间也需排尿5次以上，全天尿量达9L。发病以来精神差，烦躁，消瘦，近2周出现头痛。
此病人最合理的治疗为（）
A.胰岛素
B.精氨酸血管加压素每日400μg
C.最小有效剂量的精氨酸血管加压素
D.限制饮水
E.限制钠盐
参考答案：C
FUN TIME
Are you tired of the puzzles you usually do? Sudoku is a new choice. Sudoku consists of the Japanese characters Su (meaning “number”) and Doku (meaning “single”), but it was not invented in Japan. It was created by Howard Garnes in 1979. The puzzle was first introduced into Japan by Nikoli Puzzle Company in 1984. In 1986, Kaji Maki, the president of Nikoli made the rules strict and clear. Soon in the same year Sudoku became popular in Japan. In November 2004, The Times, a British newspaper, first printed it in the newspaper. It became an international hit in 2005. Now Sudoku becomes very popular all over the world.
The rule of the puzzle is to fill in the grids (格子) so that every row, every line and every 3×3 box has the numbers 1 to 9. Here is a Sudoku. Please relax and enjoy. It’s fun!
| 9 | 2 | 4 | 7 | 6 | 3 | 1 | 5 | 8 |
| 5 | 3 | 6 | 8 | 9 | 1 | 4 | 2 | 7 |
| X | 7 | 8 | 2 | 5 | 4 | 9 | 6 | 3 |
| 7 | 1 | 9 | 3 | 4 | 2 | 5 | 8 | 6 |
| 4 | 8 | 3 | 6 | 1 | 5 | 2 | 7 | 9 |
| 2 | 6 | 5 | 9 | 8 | 7 | 3 | 4 | 1 |
| 3 | 9 | 7 | 4 | 2 | Y | 6 | 1 | Z |
| 6 | 5 | 2 | 1 | 7 | 9 | 8 | 3 | 4 |
| 8 | 4 | 1 | 5 | 3 | 6 | 7 | 9 | 2 |
根据以上杂志专栏内容，回答下列问题。
小题1:Who created Sudoku?
A．Howard Garnes.
B．Sudoku.
C．Kaji Maki.
D．Nikoli.小题2:Which is true about Kaji Maki according to the reading material?
A．He was the boss of Nissan Company.
B．He helped to make Sudoku popular in Japan.
C．He was the president of The Times.
D．He is an American.小题3:Which is NOT true about Sudoku?
A．Sudoku wasn’t invented in Japan.
B．It was The Times that first printed Sudoku in the newspaper.
C．Each grid has more than one number.
D．It became popular around the world in 2005.小题4:In the puzzle above, what should “X” be?
A．5.
B．4.
C．3.
D．1.小题5:What should “Z” be in the puzzle?
A．8.
B．5.
C．2.
D．4.