患者男，40岁，因“无痛性肉眼血尿2个月”来诊。既往患视网膜血管瘤。有肾癌家族史。
仍诊断为VHL病的依据有（提示VHL基因测序未发现异常）。（）
A.具有明确家族史的单发视网膜血管瘤或中枢神经系统血管母细胞瘤
B.至少有2个视网膜血管瘤或中枢神经系统血管母细胞瘤
C.手术标本病理类型为透明细胞癌
D.患病年龄较早
E.肾肿瘤为双侧、多发
F.同时伴有嗜铬细胞瘤、肾癌，胰腺、附睾等部位病损
G.一个血管母细胞瘤伴内脏实质肿瘤
H.不能诊断为遗传性肾癌
参考答案：A, B, F, G
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| I never knew how well Mother could keep a trust until I was going through her things after she died. I discovered something I had 1 forgotten, something that happened to as a child. One night, as I lay in bed 2 my sisters and I had said our prayers, I recalled the events of the day and how 3 I behaved toward Mother."I must make things right before going to sleep," I thought. Quietly I 4 out of bed and picked up pencil and paper from the dresser, then tiptoed into the hall. The 5 from the living room shone dimly. I knew Mother was downstairs mending socks. I quickly 6 a note asking Mother to forgive me for being so 7 . I didn't want my brothers and sisters to know my 8 , so I added a postscript:"Please don't let anyone see this." Then I quietly moved 9 my parents' bedroom and put the letter under Mother's pillow. The next morning, when I 10 my bed after breakfast. I unexpectedly found a 11 note under my pillow. Mother wrote that she loved me and 12 me. This became my 13 of apologizing whenever I talked back or disobeyed. Mother always left a return note, but she never 14 our under-the-pillow messages in front of the family. Even when we were 15 , she never mentioned them when we brothers and sisters recalled our childhood. When mother 16 , I had to go through her personal belongings. In her desk was a bundle of notes tied with a faded ribbon. On top was a message in her handwriting. It read,"In the event of my death, please 17 these." I 18 the packet and glanced at the handwriting on the bottom. To my surprise I 19 my childish writing,"P.S. Please don't let anyone see this. Love, Edie." I gently glanced the unopened bundle in the 20 along with other things for the rubbish burner. "Lord," I prayed"make me like my mother." | ||||
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