----I didn’t realize how popular the restaurant was until I made a reservation the other day.

----I beg your pardon, but when              ?

A．was you realized it

B．it was that you realized it

C．you realized it

D．was it that you realized it

女孩10个月，面色苍白，食欲差。Hb68g/L，RBC2.8×10/L，网织红细胞1%，肝肋下2.5cm，脾肋下0.5cm。为确诊应首选的检查是（）

A.骨髓检查

B.红细胞脆性试验

C.测血清铁和总铁结合力

D.测维生素B和叶酸浓度

E.血红蛋白电泳和HbF检查