下列哪项是引起颅内压增高的主要原因（）

A.脑脊液增加

B.脑血流量增加

C.脑组织体积增加

D.颅内生理功能调节失效

E.各种颅内病变

We still couldn't decide          with our difficulties in learning English.[ ]

A. how to do      

B. how to deal        

C. what to deal      

D. what to solve