The reason why George is looking for another job is that he’s _____ his manager’s complaints.

A．put up with

B．come up with

C．kept up with

D．fed up with

30岁经产妇，第一胎分娩巨大儿。随后两次妊娠分别在24周及22周时破膜不久流产。最可能造成两次流产的原因是（）。

A.染色体异常

B.ABO血型不合

C.宫颈内口松弛

D.子宫肌瘤

E.黄体功能不足