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问题 单项选择题 A1型题

关于新药证书的说法正确的是（）

A.由国家食品药品监督管理局药品审评中心发放

B.发放新药证书的同时，要发给药品批准文号

C.国家食品药品监督管理局依据综合意见，作出审批决定，符合规定的，发给新药证书，申请人已持有《药品生产许可证》并具备生产条件的，同时发给药品批准文号

D.改变剂型但不改变给药途径，以及增加新适应证的注册申请获得批准后发给新药证书和药品批准文号

E.改变剂型但不改变给药途径，以及增加新适应证的注册申请获得批准后发给新药证书

答案

参考答案：C

改错题

改错题。

One cold winter day in 1900, a small boy calling                                                           1.________

Charlie Chaplin walking along the street in London.                                                       2.________

He did not have breakfast and lunch. He wanted to                                                       3.________

buy some bread, and he didn't have any money.                                                            4.________

His father dead when he was very young. His                                                                5.________

mother was often very sick, and she could not take                                                        6.________

care of Charlie or his brother. All of them had to                                                           7.________

work to help their sick mother.

     He was a small boy but his dream was not very big.                                                 8.________

He wanted to be great man in the world of film. So                                                       9.________

he worked very hard to sing and danced well.                                                              10.________
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问答题

甲、乙签订房屋租赁合同，双方约定：甲将其所有的房屋3间租给乙，期限为8个月，自2007年11月1日至2008年6月30日，若有一方违约，应付给对方违约金2000元。2007年12月，甲为了经营水果批发业务向银行贷款，为了获取贷款，甲将该房屋抵押给银行，并办理了抵押登记。2008年2月，甲又与丙签订了该房屋买卖合同，但甲并未将m卖房屋的事实告知乙和银行。
根据上述案情，请回答下列问题：

甲与银行之间设定的抵押权是否成立为什么
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