患者女，17岁。被别人发现颈前部肿大就诊，平时无任何自觉症状。查体：脉搏88次/分。甲状腺双侧对称性肿大、质软，随吞咽活动。

2年后患者再次就诊，主诉平卧时憋气。检查发现右侧甲状腺体有多个结节。此时的治疗应考虑（）

A.加大甲状腺素剂量

B.手术治疗

C.继续观察6个月

D.继续服用卢戈溶液

E.加大抗甲状腺药物剂量

Most people have no idea of the hard work and worry that gointothe collecting of those fascinating birds and animals that they pay to see in the zoo.One of the questions that is always asked of me is 1 I became an animal collector in the first 2.The answer is that I have always been interested in animals and zoos.According to my parents, the first word I was able to say with any 3 was not the conventional “mamma” or “daddy”,4 the word “zoo”, which I would 5 over and over again with a shrill 6 until someone, ingroupsto 7 me up, would take me to the zoo.When I 8 a little older, we lived in Greece and I had a great 9 of pets, ranging from owls to seahorses, and I spent all my spare time 10 the countryside in search of fresh specimens to 11 to my collection of pets.12 on I went for a year to the City Zoo, as a student 13 , to get experience of the large animals, such as lions, bears, bison and ostriches,14 were not easy to keep at home.When I left, I 15 had enough money of my own to be able to 16 my first trip and I have been going 17 ever since then.Though a collector's job is not an easy one and is full of 18 ,it is certainly a job which will appeal 19 all those who love animals and 20.

请在1处填上正确答案（）

A.how

B.where

C.when

D.whether