在下列各句的空白处填入一个适当的词，使句子意思完整，语法正确。

1. My daughter bought a new _________ of shoes for me.

2. I haven't _________ your letter yet. When did you send it?

3. I don't like having classes on Saturday. Me __________.

4. The traffic is busy at that time. You'd better be careful to _________ the street.

5. It is better to keep your voice down in _________ places.

以下对诊断自身免疫性肝炎意义最大的自身抗体是（）

A.RF

B.AKA

C.ANA

D.ANCA

E.ASMA