问题 单项选择题

男性,35岁,多饮多尿乏力,被诊断2型糖尿病3年,服用二甲双胍1.5g/d格列体脲(优降糖)7.5mg/d)治疗,效果欠佳,HbAlC在8%~10%间,1年来听力减退,母亲和一哥患糖尿病并耳聋。IcA(-),GAD抗体阴性,身高165cm,体重45kg。电测听示神经性耳聋。本例病人最有价值的检查是().

A.基因诊断

B.胰岛素释放试验评估胰岛B细胞功能

C.头颅CT检查

D.脑电图检查

E.胰岛素抗体检测

答案

参考答案:A

解析:年轻发病,母系遗传,肥胖不明显,口服降糖药物效果差,伴神经性耳聋病家族史,要考虑线粒体基因突变糖尿病的可能,基因诊断是最有价值的检查,本病病理生理上以胰岛素分泌进行性下降为主,治疗上需要胰岛素治疗。

阅读理解
阅读理解。
      Mr. and Mrs. Green lived in a big city, and one summer they went to the country (乡村) for their
holiday. They enjoyed it very much, because it was a quiet, clean place.
      One day they went for a walk early in the morning and met an old man. He lived on a farm, and he
was sitting in the warm sun in front of his house. Mr. Green asked him, "Do you like to live in this quiet
place?"
      The old man said, "Yes, I do."
       Mr. Green said, "What are the good things about it?" The old man answered, "Well, the people here
know each other. They often come and visit me, and I often go and visit them. And there are also lots
of children here." 
      Mr. Green said, "That's interesting. And what are the bad things?"
      The old man thought for a moment and then said, Well, the same things, really.
1. Mr. and Mrs. Green went to the country ______.
[ ]
A.to see the old man
B.to spend their holiday
C.to see the quiet place
D.to see their friends
2. Mr. and Mrs. Green enjoyed the country because ______.
[ ]
A.it was far from the city
B.it was a farm
C.it wasn't far
D.it was quiet and clean
3. Mr. and Mrs. Green took a walk ______.
[ ]
A.early in the morning
B.after breakfast
C.in the evening
D.after lunch
4. The old man said, Yes, I do. I do here means ______.
[ ]
A.I like to live in this place
B.I like to sit in the warm sun
C.I like to go out for a walk early in the morning
D.I like to live in the city.
5. Did the old man like the people to come and visit him?
[ ]
A.Yes, he did.
B.No, he didn't.
C.Sometimes he did, but sometimes he didn't.
D.We don't know.
单项选择题