—Would you mind opening the door? It's hot outside.

—___________. [ ]

A. Certainly not

B. Yes, please

C. Sorry, I won't

D. Thank you

影响龋病流行的最主要因素之一是( )

A．钙磷摄入的比例与摄入量
B．刷牙的时间与频率
C．钙的摄入量与摄入频率
D．糖的摄入量与摄入频率
E．就诊的医疗级别与次数