问题 问答题

阿司匹林的药理作用及临床应用是什么

答案

参考答案:阿司匹林为非选择性环氧酶抑制药,具有解热、镇痛、抗炎的作用:①解热镇痛及抗风湿:阿司匹林有较强的解热、镇痛作用。用于头痛、牙痛、肌肉痛、痛经及感冒发热等,能迅速减轻炎症引起的红、肿、热、痛等症状,迅速缓解风湿性关节炎的症状。大剂量阿司匹林能使风湿热症状在用药后24—48h明显好转,故可作为急性风湿热的鉴别诊断依据。②影响血小板的功能:低浓度阿司匹林不可逆地抑制血小板环氧酶,减少血小板中血栓素A2(TXA2)的生成,从而影响血小板的聚集及抗血栓形成功能,达到抗凝的作用。高浓度阿司匹林能直接抑制血管壁中前列腺素合成酶,减少前列腺素(PGI2)合成。PGI2是TXA2的生理对抗剂,它的合成减少可能促进血栓形成。血小板中前列腺素合成酶对阿司匹林的敏感性远较血管中此酶的活性高,因此,临床上采用小剂量(50—100mg)阿司匹林治疗缺血性心脏病、脑缺血病、心房颤动、人工心脏瓣膜、动静脉瘘或其他手术后的血栓形成。③儿科用于皮肤黏膜淋巴结综合征(川崎病)的治疗。

阅读理解

Deep in the Amazon forest, thousands of people still live in isolation from the rest of the world.

In a recent press release, the Brazilian government confirmed the existence of another isolated tribe of about 200 people living in the Vale do Javari reservation. The 200 people living in the Vale do Javari reservation. The reservation, located near the Peruvian border, is about the size of Portugal. At least another 14 isolated tribes, with a total population of about 2000, call the area home.

The newly observed group lives on four large straw-roofed buildings and grows corn, peanut and other crops.

Brazil’s National Indian Foundation (BNTF) first noticed the reservation in the forest using satellite maps, but it wasn’t until April that an airplane expedition was able to confirm the tribe’s existence. “The work of finding and protecting isolated groups is part of Brazilian public policy,” said the BNIF officer for Vale do Javari, Fabricio Amorim. “To confirm something like this takes years of hard work.”

BNIF estimates there are 68 isolated tribes living in the Amazon. The organization uses airplanes to avoid disturbing the tribes through personal contact, but that doesn’t mean others are so respectful of their right to privacy.

Illegal fishing, woodcutting and hunting bring people into the protected area. Oil exploration on the Peruvian side of the border is another threat. All kinds of criminals also invade the lands of the local groups, said Amorim. The outsiders can damage the land and influence the cultures of indigenous(土著的)peoples. They can also bring diseases which can wipe out the whole population that still lack even basic antibiotics(抗生素).

Brazil’s indigenous peoples won the legal right to their traditional lands in Brazil’s 1988 Constitution, which stated that all indigenous lands shall be divided and turned over to tribes within five years. Indigenous groups now control 11 percent of Brazil’s territory, including 22 percent of the Amazon.

Allowing indigenous groups the right homelands is not just a matter of human rights. The rest of the world can benefit from their knowledge. Mark Plotkin has spent years living with the people of the Amazon and learning from their traditional healers. In his lecture, he pointed out that many useful materials and knowledge, including numerous drugs, can be gained from listening to the indigenous groups of the Amazon. Besides this, they are also more effective at protecting the land, and less expensive, than hired rangers(护林人).

小题1:The underlined word in the first paragraph probably means “a state of            ”.

A.separation

B.interaction

C.satisfaction

D.excitement小题2:From the passage we can learn that the tribes in the Amazon forest             .

A.only live on a reservation designated for them

B.prefer straw-roofed buildings to wooden ones

C.keep contact with the outside world through airplanes

D.have the legal right to the land they live on小题3:Which of the following is TRUE according to Amorim?

A.Privacy violation is common among the Amazon tribes.

B.The laws dividing the lands of the tribes are far from enough.

C.Modern civilization endangers the tribes and their cultures.

D.It is hard to make public policy to protect primitive tribes.小题4:The last paragraph is mainly about              .

A.the lost human rights of the indigenous peoples

B.the benefits of protecting the primitive tribes

C.the value of traditional healing

D.the indigenous peoples as guardians of the Amazon forest

单项选择题