问题 单项选择题 A1/A2型题

环磷酰胺对何种肿瘤疗效最为显著()。

A.卵巢癌

B.急性淋巴细胞性白血病

C.肺癌

D.多发性骨髓瘤

E.恶性淋巴瘤

答案

参考答案:E

解析:环磷酰胺在体外无抗肿瘤活性,进入体内后先在肝脏中经微粒体功能氧化酶转化成醛磷酰胺,而醛酰胺不稳定,在肿瘤细胞内分解成酰胺氮芥及丙烯醛,酰胺氮芥对肿瘤细胞有细胞毒作用。环磷酰胺是双功能烷化剂及细胞周期非特异性药物,可干扰DNA及RNA功能,尤以对前者的影响更大,它与DNA发生交叉联结,抑制DNA合成,对S期作用最明显。

阅读理解

阅读短文,选择正确答案。

     Typhoons are some of the worst storms, usually around the Pacific Ocean and the South China Sea. Most

happen in July, August and September.

     How does a typhoon happen? When lots of sea water gets hot in the summer sun, it evaporates into the air.

This makes the air hotter. When the air gets warm enough, it starts to move higher up into the sky. Then,

cooler air around it rushes in. It fills the space that is left. After the air gets warmer, it starts to move quickly,

making wind. The wind goes in circles, and it keeps moving higher in the sky. The warmer the air gets, the

quicker the wind moves. And when the wind moves faster than 30 meters a second, a typhoon begins.

     A typhoon has two parts, one is called the "eye". In the eye, the wind does not move so fast. The other part

is the wall of clouds around the eye. This is where the strongest wind and hardest rains are.

     Typhoons are very dangerous. In 2004, Typhoon Yunna killed 164 people in Zhejiang, and 24 people were

missing. In May 2006, Typhoon Pearl hit Guangdong and Fujian, and thousands of houses were damaged.

     What to do when a typhoon hits:

     ● Stay inside, close all the windows and stay away from them.

     ● Try to bring all of your things inside. Strong winds could even blow away your bikes!

     ● Listen to the radio or TV for important information.

     ● If you're told to go to a safer place, do so right away.

1. Typhoons often happen ________. [ ]

A. in the hot season

B. in the cold season

C. only in China

D. under the sea

2. Which picture can tell meaning of the underlined sentences "…, it starts to move higher up into the sky.

    Then, cooler air around it rushes in."? [ ]

3. When a typhoon comes, we cannot _______. [ ]

A. close all the windows

B. listen to typhoon news

C. stay outside with our bikes

D. stay inside the strong house

4. This passage is mainly about ________. [ ]

A. the knowledge of typhoon

B. the eye of a typhoon

C. the names of typhoon

D. the most dangerous typhoon Yunna

5. Which of the following is TRUE according to the passage? [ ]

A. The warmer the air gets, the slower the wind moves.

B. This year Typhoon Pearl killed 164 people in Zhejiang.

C. The strongest winds and harder rains are in the eye of typhoon.

D. A typhoon will happen when the wind goes faster than 30 meters a second.

单项选择题