- Do you think you could do without help?

- __________. This is not the first time for me.

A．Take care

B．Hurry up

C．Not exactly

D．Not to worry

女性，7岁。易疲劳、剧烈活动气促1年余。查体：胸骨左缘2、3肋间可闻Ⅱ级SM。超声心动图检查：房间隔紧邻上腔静脉处回声脱失20mm。

宜采取的治疗是（）

A.药物治疗

B.药物治疗+介入治疗

C.介入治疗

D.介入治疗+手术修补

E.手术修补