符合粒细胞发育过程形态学演变规律的是（）

A.核染色质结构由紧密粗糙到疏松细致

B.细胞体积由小变大

C.胞质颗粒从有到无

D.核质比例由大到小

E.核仁由无到有

---Would your parents like to go to Taiwan for a vacation with you?

---They’d love to, but ______of them has enough time .

A．either

B．neither

C．none

D．both