She pretended to be calm but _______she was more than nervous at the time she was being questioned.    [ ]

A. in actual    

B. actually  

C. as matter of fact  

D. in a fact

患者女性，36岁，乏力、面色苍白半个月，尿色如浓茶，化验有贫血，血Hb68g/L，网织红细胞18%，尿常规（-），尿胆红素（-），尿胆原强阳性，血总胆红素41μmol/L，直接胆红素5μmol/L，Coombs试验（+）。该患者最有可能的诊断是（）.

A.缺铁性贫血

B.再生障碍性贫血

C.自身免疫性溶血性贫血

D.地中海贫血

E.营养不良性贫血