问题
问答题
What is oxygen dissociation curve and please describe some factors influencing this curver. (10 Points)
答案
参考答案：
Oxygen dissociation curve: The graph of the relationship between the partial pressure of oxygen and the degree of hemoglobin saturation with oxygen, which has a characteristic sigmoid shape. [2`]
Influencing factors: pH value, PCO2, temperature and 2,3-diphosphoglycerate (2,3-DPG). [4`]
Increase of [H+], PCO2, temperature and 2,3- DPG will induce the curve right shift and more O2 release from Hb for tissue use [2`]
while decrease of mentioned–above factors will trigger the curve left shift and more O2 combination with Hb [2`].