It was ______ in the exam that ______ how much time I had wasted. 

A．not until I failed;I realized

B．until I failed; I didn’t realize

C．not until I failed; did I realize

D．until I failed; I realized

麻痹性痴呆病理变化，不正确的是（）

A.涉及范围广泛，性质复杂

B.仅侵犯大脑实质和脑膜

C.以炎性及变性改变为主要特征

D.病变程度以额叶最为显著

E.大脑皮质中可发现游离铁质沉着和螺旋体