问题 问答题

一氧化碳中毒的机制、临床表现是什么?

答案

参考答案:

CO中毒主要引起组织缺氧。CO吸入体内后,85%与血液中红细胞的血红蛋白(Hb)结合,形成稳定的COHb。CO与Hb的亲和力比氧与Hb的亲和力大240倍。吸入较低浓度CO即可产生大量COHb。COHb不能携带氧,且不易解离,是氧合血红蛋白(02Hb)解离速度的l/3600。COHb的存在还能使血红蛋白氧解离曲线左移。血氧不易释放给组织而造成细胞缺氧。 

临床表现: 

轻度中毒:头痛、头晕、头胀、耳鸣、恶心、呕吐、心悸、站立下稳,有短暂的意识模糊。 

中度中毒:除上述症状加重外,颜面潮红,口唇呈樱桃红色,脉快多汗,步态蹒跚,嗜睡,甚至昏迷。 

重度中毒:除昏迷外,主要表现有各种反射明显减弱或消失,大小便失禁,四肢厥冷,口唇苍白或紫绀,大汗,体温升高,血压下降,瞳孔缩小、不等大或扩大;呼吸浅表或出现潮式呼吸。可发生严重并发症,如脑水肿、肺水肿、心肌损害、休克、酸中毒及肾功能不全等。

单项选择题
单项选择题

The telecommunications, pharmaceutical, and airline industries all have undergone radical changes in recent years. Pharmaceutical companies, which once sold drugs to the doctors that dispensed them, switched to the solution-selling method and started dealing with health-care companies. And many major airlines consolidated at the same time that low-cost firms like Jet Blue entered the market.

In each of these industries, the game changed, and with new rules came new ways to win. That is the premise of Harvard Business School’s "Changing the Game. Negotiation and Competitive Decision Making." The program, which covers not only deal-making but also topics as diverse as online auctions and strategic partnerships, "is for companies that are going through fundamental change in the way things are done," says Max Bazerman, program chair and professor of business administration at the school.

This is not a program for novices, says Bazerman; most participants have already attended a general negotiation program. In "Changing the Game," participants learn to understand their thought processes regarding negotiation, to compare rational and intuitive decision-making strategies, and to identify common mistakes made by even the most experienced professionals. By focusing on competitive environments, the program draws on some of the most advanced concepts from the emerging areas of behavioral economics, behavioral decision research, and behavioral finance.

Participants engage in simulated negotiations that highlight the tension between creating and assessing value, and learn how to think about both simultaneously. The soup-to-nuts simulations encompass preparation, team building, negotiating, and feedback, as well as the development of a conceptual structure for thinking about negotiations more rationally. Participants then apply that structure in their critiques of several large-scale negotiation cases. Ultimately participants apply their newly-honed analytic skills to their own companies and critique of past negotiations.

Negotiations can take many forms, of course. Bazerman notes that auctions are becoming increasingly common. Thanks to a renewed focus on driving clown costs, auctions have emerged as a valuable way for buyers to exert maximum leverage (although the course offers advice to sellers as well). Here again, coursework focuses both on analysis of case studies and on simulations that give participants a chance to roll up their sleeves and put themselves to the test.

"Max’s approach is more pragmatic than other programs I’ve taken," says Gerry Dully, senior vice president of global marketing and logistics at Methanex, a producer of methanol based in Vancouver. "Looking at my prior experience, I could see what mistakes I made, and I’m more conscious of them now. The course had a profound impact on how I’ve modified my behavior in negotiating situations.

What is the focus of Harvard Business School’s training program()

A. Online auctions

B. Strategic partnership

C. Business management

D. Negotiation