问题
多项选择题
米托坦(mitotane)的药理作用及用途
A.用于不能切除的肾上腺皮质癌或皮质癌术或辅助治疗
B.选择性使肾上腺皮质球状带细胞萎缩,坏死
C.选择性使肾上腺皮质束状带和网状带萎缩,坏死
D.抑制11β-羟化反应,干扰11-去氧皮质醇分别转化为可的松和氢化可的松
E.抑制可的松与泼尼松分别转化为氢化可的松和泼尼松龙发挥作用
答案
参考答案:A,C
米托坦(mitotane)的药理作用及用途
A.用于不能切除的肾上腺皮质癌或皮质癌术或辅助治疗
B.选择性使肾上腺皮质球状带细胞萎缩,坏死
C.选择性使肾上腺皮质束状带和网状带萎缩,坏死
D.抑制11β-羟化反应,干扰11-去氧皮质醇分别转化为可的松和氢化可的松
E.抑制可的松与泼尼松分别转化为氢化可的松和泼尼松龙发挥作用
参考答案:A,C
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