The country life he was accustomed to ______ a lot since 1998. [ ]

A. change

B. has changed

C. changing

D. had changed

TN心脏病中，不宜使用血管扩张药的是：（）

A.二尖瓣关闭不全

B.肺动脉高压

C.主动脉瓣关闭不全

D.高血压性心脏病

E.心包压塞征