A

题目分析：考查固定搭配。如何处理sth：how to deal with sth; what to do with sth；句意：你该如何处理这件事情？你又会怎么做？故A正确。

点评：如何处理sth：how to deal with sth; what to do with sth；因为deal是不及物动词，后面接介词with，构成固定搭配；do是及物动词，what作为它的逻辑宾语。