患者女，35岁。双腕、双手指间关节、掌指关节、双膝关节肿痛1年，晨僵2小时。查体见双手近端指间关节梭形肿胀，双腕关节肿，活动轻度受限。化验RF300IU/ml，ESR50mm/h。

适宜此患者的治疗方案是 （）

A.单用非甾体抗炎药

B.激素+非甾体抗炎药

C.非甾体抗炎药+甲氨蝶呤

D.非甾体抗炎药+柳氮磺吡啶

E.非甾体抗炎药+生物制剂+甲氨蝶呤+柳氮磺吡啶

So long as teachers fail to distinguish(differ) between teaching and learning, they will continue to undertake to do for children that which only children can do for themselves. Teaching children to read is not passing reading on to them. It is certainly not endless hours spent in activities about reading. Douglas insists that "reading cannot be taught directly and schools should stop trying to do the impossible".
Teaching and learning are two entirely different processes. They differ in kind and function. The function of teaching is to create the conditions and the climate that will make it possible for children to plan cleverly the most efficient system for teaching themselves to read. Teaching is also a public activity: It can be seen and observed.
Learning to read involves all that each individual does to understand the world of printed language. Almost all of it is private, for learning is an occupation of the mind, and that process is not open to public scrutiny.
If teacher and learner roles are not interchangeable, what then can be done through teaching that will aid the child in the long search for knowledge Smith has one principle rule for all teaching instructions. "Make learning to read easy, which means making reading a meaningful, enjoyable and frequent experience for children. "
When the roles of teacher and learner are seen for what they are, and when both teacher and learner fulfill them properly, then much of the pressure and feeling of failure for both is got rid of. Learning to read is made easier when teachers create an environment where children are given the chance to solve the problem of learning to read by learning.

The teaching of reading will be successful if ______.

A. teachers can make their teaching activities observable
B. teachers can teach their students how to read
C. teachers can improve conditions at school for the students
D. teachers can enable students to develop their own way of reading