问题 多项选择题 案例分析题

患者男,52岁,因“乏力1个月”来诊。近1个月体力下降明显,轻微活动出现气促、心悸。既往无肝炎病史。查体:T36.8℃;重度贫血貌,消瘦,浅表淋巴结未触及,皮肤、黏膜无黄染;胸骨可疑压痛,HR109次/min,律齐,双肺呼吸音清;肝肋下2cm,脾肋下平脐;双下肢水肿。

结合目前患者情况以及治疗进展,下一步可以选择的治疗包括(提示:治疗1个月后症状明显改善,脾回缩至肋下2cm。)()

A.沙利度胺或雷那度胺

B.去甲基化药物

C.组蛋白去乙酰酶抑制药

D.脾放射治疗

E.脾切除

F.造血干细胞移植

答案

参考答案:A, D, F

选择题
阅读理解

阅读理解。

     Every baby born a decade from now will have its genetic code (基因编码) mapped at birth, the head of

the worlds' leading genome sequencing (基因图谱) company has predicted.

     A complete DNA read-out for every newborn will be technically possible and affordable in less than five

years, promising a revolution in healthcare, says Jay Flatley, the chief executive of Illumina. Only social and

legal problems are likely to delay the age of "genome sequences," or genetic profiles. By 2019 it will have

become routine to map infants' genes when they are born, Dr Flatley told The Times.

     This will open a new approach to medicine, by which conditions such as high blood pressure and heart

disease can be predicted and prevented and drugs used more safely and effectively.

     A baby's genome can be discovered at birth by a blood test. By examining a person's genome, it is possible

to identify raised risks of developing diseases such as cancers. Those at high risk can then be screened more

regularly, or given drugs or dietary advice to lower their chances of becoming ill.

     Personal genomes could also be used to ensure that patients get the medicine that is most likely to work

for them and least likely to have side-effects.

     The development, however, will raise legal concerns about privacy and access to individuals' genetic

records.

     "Bad things can be done with the genome. It could predict something about someone-and you could

possibly hand the information to their employer or their insurance company," said Dr Flatley.

     "People have to recognize that this horse is out of the barn, and that your genome probably can't be

protected, because everywhere you go you leave your genome behind. Complete genetic privacy, however,

is unlikely to be possible", he added.

     As the benefits become clearer, however, he believes that most people will want their genomes read and

interpreted. The risk is nothing compared with the gain.

1. In the first two paragraphs, the author mainly wants to tell us about _____. [ ]

A. the significant progress in medicine

B. the promise of a leading company

C. the information of babies' genes

D. the research of medical scientists

2. Which of the following is a problem caused by this approach? [ ]

A. The delaying in discovering DNA. 

B. The risk of developing diseases at birth.

C. The side-effects of medicine on patients.

D. The letting out of personal genetic information.

3. What does the underlined sentence "... this horse is out of the barn" mean? [ ]

A. Genetic mapping technique has been widely used. 

B. Genetic mapping technique is too horrible to control.

C. People are eager to improve genetic mapping technique.

D. People can't stop genetic mapping technique advancing.

4. What's Dr Flatley's attitude towards the technology? [ ]

A. Tolerant.

B. Conservative.

C. Positive.

D. Doubtful.