— Tom was late for work this afternoon.

— _____？As far as I know, he is fairly punctual.

A．Why not

B．So what

C．How come

D．How about

国家对药品经营企业实行

A．许可证的验证制度

B．许可证的管理制度

C．合格证的认证制度

D．许可证的年检制度

E．许可证的有效期限管理制度和年检制度