甲房地产开发企业将其开发的某住宅小区项目委托乙房地产经纪机构代理销售，并签订了委托销售合同，合同约定另外三家房地产经纪机构也可以销售该项目，但不直接与甲房地产开发企业签订委托销售合同。乙房地产经纪机构给甲房地产开发企业提交的营销方案中，关于销售价格的部分内容为：按估算的开发成本和25%加成率测算的价格为5600元／m2，开盘时确定的均价为5800元／m2，开盘以后原则上每个季度调升一次价格，每次调升的幅度不超过3%；当地同类房地产的市场均价为8000元／m2。对于楼层、整单元、整栋购买的消费者，价格优惠5%；对于一次性付款的消费者，价格优惠3%；对抵押贷款的消费者，价格优惠1%。
乙房地产经纪机构向甲房地产开发企业提交营销方案之前应完成的工作为（）。
A.与甲房地产开发企业签订委托销售合同
B.向甲房地产开发企业索取相关资料
C.进行销售准备
D.与甲房地产开发企业进行项目结算
参考答案：A, B
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| The steep rise in breast cancer over the past fifty years has been blamed on a variety of causes--from late childbearing to pesticides. Now Belgian scientists have evidence that it may be caused by teenagers drinking fizzy soft drinks instead of weak beer. At a meeting in Brussels last week, Jack Janssens of the Limburg University Centre in Diepenbeek described experiments in which teenagers fasted for 12 hours then drank a 330-millilitre bottle of a popular fizzy drink--he won’t divulge the brand--or a bottle of "table beer", a drink containing 1.1 per cent alcohol that was popular in Belgium before soft drinks came on the market. The beer is still served in Belgian hospitals, especially to new mothers. The focus of the study was insulin, the hormone that regulates blood sugar levels. As expected, insulin levels shot up after teenagers drank the sugar-laden soft drinks, but not after the beer, which although it contains complex carbohydrates has few simple sugars. "What was really a new observation," says Janssens, "was that the fatter the teenager was, the more the insulin went up." The insulin levels did not depend on the level of blood sugar or the total weight of an individual, just obesity. Janssens thinks insulin is a key factor in the development of the human breast, because it influences levels of several other hormones, including growth factor, sex steroids and their inhibitory binding proteins. Inappropriate secretion of insulin at a critical phase of development, he says, "might induce lesions in the breast cells leading to breast cancer later in life". He believes his research suggests a vicious circle in which "soft drinks and high caloric foods in pubertal children brings accumulation of body fat and in turn increases the response of insulin". This could lead to loss of sensitivity to insulin, which may have a continuing effect on breast cells. "A history of weight gain in early adult life is associated with an increased breast cancer risk in Western women," says Janssens. Insulin may be the link. In males, a similar effect may lead to testicular or prostate cancer. As for the beer, Janssens couldn’t detect any alcohol in the teenagers’ blood, which shows that they metabolise it efficiently, he says. While insulin may play a role in cancer, he says more epidemiological research is required before blaming soft drinks. Denise Baxter of Brewing Research International in Nuffield, Surrey, also told the meeting that as well as vitamin B, beer contains other anti-cancer nutrients, including antioxidants. The meeting was organised by the Confederation of European Brewers. |
What might lead to breast cancer
A．Inappropriate secretion of insulin.
B．Inhibitory binding proteins.
C．Sex steroids.
D．Sugar-laden soft drinks.