问题 单项选择题 B型题

与其他抗真菌药无交叉耐药性的棘白霉素类抗真菌药是()。

A.两性霉素B

B.卡泊芬净

C.氟胞嘧啶

D.阿糖胞苷

E.酮康唑

答案

参考答案:B

解析:

1.酮康唑可抑制肝药酶CYP3A4,药物相互作用多。

2.两性霉素B的肾毒性较大,限制其临床应用,经过改造,开发出了脂质体两性霉素B,在两性霉素B分子的外面包裹了生物脂质体,其进入体内可直接结合至真菌的感染灶,在吸附于真菌细胞膜表面后,真菌产生的磷脂酶能水解其中的脂质,使两性霉素B逸出。渗入机体,并以高浓度集中于该处组织,杀灭真菌。

3.棘白菌素抗真菌药主要有卡泊芬净、米卡芬净,和其他抗真菌药物之间无交叉耐药,因此对唑类药耐药的真菌仍有效;耐受性好,不良反应少,药物相互作用少。

阅读理解

阅读理解。

     I once had my Chinese MBA students brainstorming on "two-hour business plans". I separated them

into six groups and gave them an example:a restaurant chain. The more original their idea, the better, I said.

Finally, five of the six groups presented plans for restaurant chains. The sixth proposed a catering (餐饮)

service. Though I admitted the time limit had been difficult, I expressed my disappointment.

     My students were middle managers, financial analysts and financiers from state-owned enterprises and

global companies. They were not without talent or opinions, but they had been shaped by an educational

system that rarely stressed or rewarded critical thinking or inventiveness. The scene I just described came

in different forms during my two years' teaching at the school. Papers were often copied from the Web and

the Harvard Business Review. Case study debates were written up and just memorized. Students frequently

said that copying is a superior business strategy, better than inventing and creating. 

     In China, every product you can imagine has been made and sold. But so few well-developed marketing

and management minds have been raised that it will be a long time before most people in the world can

name a Chinese brand.

     With this problem in mind, partnerships with institutions like Yale and MIT have been established. And

then there's the "thousand-talent scheme": this new government program is intended to improve technological

modernization by attracting top foreign-trained scientists to the mainland with big money. But there are worries

about China's research environment. It's hardly known for producing independent thinking and openness, and

even big salary offers may not be attractive enough to overcome this.

     At last, for China, becoming a major world creator is not just about setting up partnerships with top

Western universities. Nor is it about gathering a group of well-educated people and telling them to think

creatively. It's about establishing a rich learning environment for young minds. It's not that simple.

1. Why does the author feel disappointed at his students? [ ]

A. Because there is one group presenting a catering service.

B. Because the six groups made projects for restaurant chains.

C. Because all the students copied a case for the difficult topic.

D. Because the students' ideas were lacking in creativeness.

2. Which of the following scenes is NOT considered as lack of creation? [ ]

A. Papers were often downloaded from the Internet.

B. Students often said that copying is a preferable business strategy.

C. Students combine knowledge and critical thoughts to solve a problem.

D. Case study debates were written up as well as recited.

3. The underlined word "scheme" in the fourth paragraph means _____. [ ]

A. timetable

B. theme

C. project

D. policy

4. We can infer from the passage that _____. [ ]

A. China can make and sell any product all over the world

B. high pay may not solve the problem of China's research environment

C. cooperation with institutions has been set up to make a Chinese brand

D. the new government program are aimed at encouraging imagination

5. Which is the best title of the passage?  [ ]

A. Look for a New Way of Learning

B. Reward Creative Thinking

C. How to Become a Creator

D. Establish a technical Environment

单项选择题