A client receiving morphine for long-term pain management develops tolerance. When the client asks the nurse what it means, which of the following should the nurse response
A. "Tolerance is an allergic reaction to a medication. "
B. "Tolerance is an ability to take the same drug for extended periods of time. "
C. "Tolerance is an increased response to a medication. "
D. "Tolerance is a diminished response to a drug so that more is required to reach the same effect. "
参考答案：D
解析：Tolerance occurs when the body requires higher doses of substances, such as alcohol, opioids, or benzodiazepines, to achieve desired effects. Increased response indicates a need for less of a drug to achieve the same effects. Allergic reactions are autoimmune responses to a particular drug or class of drugs.