Before bowel surgery, the infant is to receive oral neomycin for 3 days. The appropriate pediatric dosage of neomycin sulfate is 10. 3 mg/kg q 4 hours. The infant weighs 15 pounds, 6.4 ounces. Which of the following dosages most closely approximates a safe daily dose
A. 50 mg/day.
B. 150 mg/day.
C. 280 mg/day.
D. 430 mg/day.
参考答案:D
解析:The dose is calculated by first determining the weight in kilograms: 15 pounds, 6.4 ounces is equal to 15. 4 pounds; 15.4 pounds divided by 2.2 is equal to 7 kg. Multiplying 10.3 mg by 7 kg equals 72.1 mg. In computing a daily dosage, the dose is multiplied by the number of times it will be given per day (72.1 mg×6=432.6 mg/day).