从下面方框中选出与下列各句划线部分意思相同或相近、并能替换划线部分的选项。(共4小题，每小题1分；计4分)

(    )小题1:The careless boy didn’t pass the math exam．

(    )小题2:You’d better ask Mark．He often comes up with good ideas．

(    )小题3:The desk is so heavy that I can’t move it by myself．

(    )小题4:If you continue playing computers all day，you will sure disappoint your teachers and parents．

腺垂体功能减退症常最早出现的临床表现是（）

A.皮肤色素沉着

B.泌乳-闭经

C.继发性糖尿病

D.产后无乳汁，长期闭经不育

E.直立性头晕，低血压