—He was early drowned in a pool.—Oh, when was ______ exactly?

— It was in 1983 _______ he was swimming with his friends.

A．this; that

B．that; when

C．that; that

D．what; when

患者女性，45岁，1周前发现有乳外上象限结节，直径约1.5cm，较硬，活动，无压痛，两侧乳腺对称， * * 及皮肤无特殊，两侧腋下均未及淋巴结，患乳无炎症或创伤史，钼靶拍片X线检查发现患乳有细小钙化点。

保乳术的适应证包括（）。

A.单发病灶

B.肿块<3cm

C.妊娠期乳腺癌

D.病变位于乳晕外

E.患者自愿

F.以上均对