问题 多项选择题 X型题

关于药物的溶出速率方面的叙述正确的是()

A.可用Noyes-Whitney方程表示

B.溶出速度与溶出速度常数k、药物粒子的表面积S、药物的溶解度Cs成正比

C.提高药物的溶出速率,可通过增大药物的溶解度解决

D.增大药物表面积(颗粒大小等)可增加溶出速率

E.可用Higuchi方程来解释

答案

参考答案:A, B, C, D

解析:Noyes-Whitney方程dC/df=kS(Cs-C)解释影响药物溶出速率的诸因素,表明药物从固体剂型中的溶出速度与溶出速度常数k、药物粒子的表面积S、药物的溶解度Cs成正比。因此提高药物的溶出速率,可通过增大药物的溶解度(搅拌速度、温度、介质的性质等)和增大药物表面积(颗粒大小等)来解决。

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Part 4


Questions 26-45


·Read the following passage and decide which answer bestfits each space.
·For questions 26-45, mark one letter A, B, C or D on the Answer Sheet.
The "standard of living" of any country means the (26) person’s share of the goods and services which the country produces. A country’s standard of living, therefore depends (27) and foremost on its capacity to produce wealth. "Wealth" in this (28) is not money, for we do not live on money (29) on things that money can buy: "goods" such as food and clothing, and "services" such as (30) and "entertainment".
A country’s capacity to produce wealth depends upon many factors, most of which have an effect (31) one another. Wealth depends (32) a great extent upon a country’s natural resources. Some regions of the world are well supplied with coal and minerals, and have a (33) soil and a favorable climate; other regions (34) none of them.
Next to natural resources (35) the ability to turn them to use. China is perhaps as well off as the USA in natural resources, but suffered for many years from (36) and external wars, and for this and other reasons was incapable (37) her resources. Sound and (38) political conditions, and freedom from foreign invasion, enable a country to develop its natural resources peacefully and steadily, and to produce more wealth than another country (39) well served by nature but less well ordered.
A country’s standard of living does not only depend upon the wealth that is produced and (40) within its own borders, but also upon what is indirectly produced through international trade. For example, Britain’s wealth in foodstuffs and other agricultural products would be much (41) if she had to depend only on those grown at home. Trade makes it possible for her surplus manufactured goods to be traded abroad for the agricultural products that would (42) be lacking. A country’s wealth is, therefore, much (43) by its manufacturing capacity, (44) that other countries can be found ready to (45) its manufactures.

A.robust

B.sturdy

C.p

D.stable