— My brother hurt his legs when he rode his bike on the way back home.

— ______.

A．that’s too bad

B．he is very careless

C．be careful next time

D．I’m sorry to hear that

浸润性尿路上皮癌提示预后不良的组织学变型有（）。

A.尿路上皮癌伴鳞状分化

B.尿路上皮癌伴腺样分化

C.微 * * 变型

D.淋巴上皮瘤样变型

E.微囊变型