_________ many times, but he still couldn’t understand it.

A．Having been told

B．Though he had been told

C．He was told

D．Having told

8岁女孩。不规则发热18d，伴头痛、呕吐2周。近1周来视力减退，颈有阻力，克氏征阳性，布氏征阳性，心肺无异常。脑脊液压力增高，白细胞数350×10⁶/L，中性粒细胞28%，淋巴细胞72%，糖2.3 mmol/L，氯化物%mmol/L，蛋白定性＋＋，定量1.0 g/L。给予抗生素和抗结核治疗无效。

该病例临床诊断首先考虑的是

A．耐药结核菌性脑膜炎

B．化脓性脑膜炎

C．治疗不规则的化脓性脑膜炎

D．脑脓肿

E．隐球菌性脑膜炎