After watching a movie Avatar, Mary lay in bed with her eyes ______ open

while all her family were ______ asleep．

A．wide; sound

B．wide; soundly

C．widely; sound

D．widely; soundly

药物的血浆半衰期是指

A．药物的稳态血浓度下降一半的时间

B．药物的有效血浓度下降一半的时间

C．药物的血浆蛋白结合率下降一半时间

D．药物的血浆浓度下降一半的时间

E．以上都不是