以下提供若干组考题，每组考题共用在考题前列出的A、B、C、D、E五个备选答案。请从中选择一个与问题关系最密切的答案，某个备选答案可能被选择一次、多次或不被选择。

核酸中核苷酸间的连接方式

A．肽键
B．磷酸二酯键
C．磷酸酯键
D．酯键
E．糖苷键

Oh, this is really a big shop. Do you know when it       ?[ ]

A. built                  

B. was built

C. has built                    

D. has been built