问题 读图填空题

1975年科学家首次利用B淋巴细胞杂交瘤技术制备出单克隆抗体。请根据下图回答问题:

(1)病原体注入小鼠体内后,要经过________细胞的处理后形成抗原-MHC复合体,才能被免疫细胞识别。

(2)制备单克隆抗体所用的B淋巴细胞一般从脾中采集,然后以__________作诱导剂,使B淋巴细胞和骨髓瘤细胞融合。通过筛选和克隆培养,获得的杂交瘤细胞具有_________的特点。

(3)单克隆抗体的特点是____________。根据上图写出应用杂交瘤技术获得单克隆抗体的两种主要方法______________。

答案

(1)吞噬(或巨噬) 

(2)灭活的仙台病毒或聚乙二醇      既能产生特异抗体,又能无限增殖

(3)特异性强,纯度高(或专一性强、灵敏度高)      体外培养法和动物体内培养法

阅读理解

Treatment for HIV has become more widespread, especially in poorer countries. It's also become cheaper, as medicine companies have lowered their prices for life-saving anti-retroviral drugs(抗逆转录病毒药物). But these drugs are still expensive and many countries are looking to create the biggest impact with limited resources. That's where World Health Organization guidelines come in, says Rochelle Walensky, a disease researcher from Harvard.

Walensky and her colleagues used computer programs to model the most cost-effective disease interventions(干预), as well as collected data from clinics in Africa and India about what works best. They found that among the choices of what to do first, earlier anti-retroviral therapy (疗法)improved five-year survival dramatically and resulted in the longer life expectancy. But cost-effective doesn't always mean affordable, especially for governments in poor countries. Countries still have to make difficult choices about how much treatment they can afford.

People in Nairobi, Kenya on Thursday, Dec. 9, 2010, protest a potential free trade area agreement between the EU and India that could see cheap anti-AIDS drugs phased out(逐步淘汰). However, Walensky notes that first-line anti-retrovirals—those medicine given to newly diagnosed patients that can keep away from symptoms for years - are much cheaper than they were a decade ago. "Second-line therapy have come down quite a bit but not to the level of first-line and countries are having a hard time affording them and increasingly over time, people are going to fail first-line therapy and they're going second-line therapy and then, eventually, they're going to need third-line therapy, some of them."

According to Walensky, history has shown that drug prices can come down when international pressure is applied to drug makers. But for now, she says, countries should focus on treating as many people as they can, as early as possible

Her paper is published in the online journal PLoS Medicine.

小题1: Which is the best title for the passage?

A.HIV Has Spread in Poorer Countries

B.Rochelle Walensky’s Life

C.International Pressure to Drug Makers

D.Early HIV Treatment Saves Lives小题2: Which of the following is TRUE according to the passage?

A.Anti-retroviral drugs have become cheap now.

B.The cost-effective treatment may be a heavy expense.

C.Cheap anti-AIDS drugs have been phased out .

D.First-line therapy deals with the most severe disease.小题3: The research is done by         .

A.using computer programs and collecting data from clinics

B.giving medicine to newly diagnosed patients with AIDS

C.urging countries to focus on treating more patients earlier

D.publishing her paper in the online journal PLoS Medicine小题4: The passage serves as a(n)___________ to Rochelle Walensky 's study.

A.assessment

B.comment

C.introduction

D.background

单项选择题