参考答案：C

解析：[分析] 动词辨析Kill 在本句中表示：令某人烦恼、伤心、关注(与annoy同义)；例：It kills me to see him working so hard. 看到他工作那么辛苦我很担心。A. made the audience langh to death使观众笑到死；B. made the audience unimaginative 使观众感到无趣；C. made the audience very painful 令观众感到痛苦；D. made the audience very nervous 令观众感到紧张；因此C为答案。