大面积烧伤儿童，口渴、尿少，尿比重1．030，脉搏140次／分，神志淡漠，肢体冷，首要的处理应是（）

A.清创

B.给予吗啡止痛

C.给予强心剂

D.创面涂抗菌药物

E.静脉快速补液

Great changes _________ in my hometown and a lot of factories ___________.

A．have been taken place; are being set up

B．have taken place ; have been set up

C．are taken place ; had been set up

D．had taken place; will be set up